Current status of domestic therapeutic radiopharmaceuticals


Release time:

Aug 30,2022

In the past, radiopharmaceuticals were often used in the diagnosis of lesions and in the instrumental examination of PET-CT and SPECT. Radiopharmaceuticals are synthesized by labeling with radionuclides to target compounds. In diagnostic use, patients need to record their positions and changes in the body through an in vitro monitoring gamma ray device after taking radiopharmaceuticals to understand the lesions. The therapeutic radiopharmaceuticals have the same function of locating the lesions. After the radionuclide-labeled drugs are specifically bound to the lesions, they can use radioactivity to continuously kill the surrounding cells.

Radiopharmaceuticals refer to a class of special drugs containing radionuclides for medical diagnosis and treatment. A radionuclide-labeled compound or biological agent used for medical diagnosis or treatment in the body. Divided into diagnostic radiopharmaceuticals and therapeutic radiopharmaceuticals.

In the past, radiopharmaceuticals were often used in the diagnosis of lesions and in the instrumental examination of PET-CT and SPECT. Radiopharmaceuticals are synthesized by labeling with radionuclides to target compounds. In diagnostic use, patients need to record their positions and changes in the body through an in vitro monitoring gamma ray device after taking radiopharmaceuticals to understand the lesions. The therapeutic radiopharmaceuticals have the same function of locating the lesions. After the radionuclide-labeled drugs are specifically bound to the lesions, they can use radioactivity to continuously kill the surrounding cells.

In recent years, the state has encouraged the development of the medical isotope industry. In addition to the use of diagnostic radiopharmaceuticals, therapeutic radiopharmaceuticals have been slowly developed. Among the drugs on the market in China, a total of 7 drugs belong to this category, among which radium chloride [223Ra] injection and yttrium [90Y] microsphere injection are only imported drugs.

The market situation of therapeutic radiopharmaceuticals

The global sales of therapeutic radiopharmaceuticals continued to grow, especially in 2020, reaching US$1.79 billion, with a compound growth rate of 14.9% from 2016 to 2020. ; Sales peaked in 2019, with a total of 566,000 doses sold, a CAGR of 14%.